BDBM50003183 (diastereomer-1)[1-(7-Cyclohexylmethyl-6-hydroxy-3-morpholin-4-ylmethyl-5,9,13-trioxo-1,4-dioxa-8-aza-cyclotridec-10-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid tert-butyl ester::(diastereomer-2)[1-(7-Cyclohexylmethyl-6-hydroxy-3-morpholin-4-ylmethyl-5,9,13-trioxo-1,4-dioxa-8-aza-cyclotridec-10-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid tert-butyl ester::CHEMBL339673

SMILES CC(C)(C)OC(=O)NC(Cc1ccccc1)C(=O)N[C@H]1CCC(=O)OCC(CN2CCOCC2)OC(=O)[C@H](O)[C@H](CC2CCCCC2)NC1=O

InChI Key InChIKey=IEYBVWBXMQBTAO-VLHRWJQDSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50003183   

TargetRenin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003183((diastereomer-1)[1-(7-Cyclohexylmethyl-6-hydroxy-3...)
Affinity DataIC50:  17nMpH: 7.4Assay Description:Inhibitory activity against human renin inhibition (at pH 7.4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003183((diastereomer-1)[1-(7-Cyclohexylmethyl-6-hydroxy-3...)
Affinity DataIC50:  17nMpH: 7.4Assay Description:Inhibitory activity against human renin inhibition (at pH 7.4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed