BDBM50003739 (Lactone3)N-[4-(4-Guanidino-phenyl)-6-methylene-2-oxo-tetrahydro-pyran-3-yl]-benzamide::CHEMBL134927

SMILES [#7]\[#6](-[#7])=[#7]\c1ccc(cc1)-[#6]-1-[#6]-[#6](=[#6])-[#8]-[#6](=O)-[#6]-1-[#7]-[#6](=O)-c1ccccc1

InChI Key InChIKey=DAGLKJZKVSWYJY-UHFFFAOYSA-N

Data  3 KI  2 Koff

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50003739   

TargetChymotrypsinogen A(Bos taurus (bovine))
University of Illinois

Curated by ChEMBL
LigandPNGBDBM50003739((Lactone3)N-[4-(4-Guanidino-phenyl)-6-methylene-2-...)
Affinity DataKi:  460nMAssay Description:Compound was tested for its binding affinity against the enzyme alpha-chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Illinois

Curated by ChEMBL
LigandPNGBDBM50003739((Lactone3)N-[4-(4-Guanidino-phenyl)-6-methylene-2-...)
Affinity DataKi:  6.00E+3nMAssay Description:Compound was tested for its binding affinity against the enzyme Urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
University of Illinois

Curated by ChEMBL
LigandPNGBDBM50003739((Lactone3)N-[4-(4-Guanidino-phenyl)-6-methylene-2-...)
Affinity DataKi:  1.00E+4nMAssay Description:Compound was tested for its binding affinity against the enzyme trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
University of Illinois

Curated by ChEMBL
LigandPNGBDBM50003739((Lactone3)N-[4-(4-Guanidino-phenyl)-6-methylene-2-...)
Affinity DataKon:  0.000250M-1s-1Assay Description:Compound was tested for its binding affinity against the enzyme trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Illinois

Curated by ChEMBL
LigandPNGBDBM50003739((Lactone3)N-[4-(4-Guanidino-phenyl)-6-methylene-2-...)
Affinity DataKon:  0.0000330M-1s-1Assay Description:Compound was tested for its binding affinity against the enzyme Urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed