BDBM50003742 (Lactone1)N-[4-(6-Methylene-2-oxo-tetrahydro-pyran-3-yl)-benzyl]-guanidine::CHEMBL335908::N-[4-(6-Methylene-2-oxo-tetrahydro-pyran-3-yl)-benzyl]-guanidine

SMILES NC(=N)NCc1ccc(cc1)C1CCC(=C)OC1=O

InChI Key InChIKey=UMOBBFIXDWSJPG-UHFFFAOYSA-N

Data  3 KI  4 Koff

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50003742   

TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Illinois

Curated by ChEMBL
LigandPNGBDBM50003742((Lactone1)N-[4-(6-Methylene-2-oxo-tetrahydro-pyran...)
Affinity DataKi:  350nMAssay Description:Compound was tested for its binding affinity against the enzyme Urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University of Illinois

Curated by ChEMBL
LigandPNGBDBM50003742((Lactone1)N-[4-(6-Methylene-2-oxo-tetrahydro-pyran...)
Affinity DataKi:  3.79E+4nMAssay Description:Compound was tested for its binding affinity against the enzyme thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
University of Illinois

Curated by ChEMBL
LigandPNGBDBM50003742((Lactone1)N-[4-(6-Methylene-2-oxo-tetrahydro-pyran...)
Affinity DataKi:  4.66E+5nMAssay Description:Compound was tested for its binding affinity against the enzyme plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University of Illinois

Curated by ChEMBL
LigandPNGBDBM50003742((Lactone1)N-[4-(6-Methylene-2-oxo-tetrahydro-pyran...)
Affinity DataKon:  0.000100M-1s-1Assay Description:Rate constant of deacylation for thrombinMore data for this Ligand-Target Pair
In DepthDetails
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Illinois

Curated by ChEMBL
LigandPNGBDBM50003742((Lactone1)N-[4-(6-Methylene-2-oxo-tetrahydro-pyran...)
Affinity DataKon:  0.000733M-1s-1Assay Description:Rate constant of deacylation for Urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Illinois

Curated by ChEMBL
LigandPNGBDBM50003742((Lactone1)N-[4-(6-Methylene-2-oxo-tetrahydro-pyran...)
Affinity DataKon:  0.000730M-1s-1Assay Description:Compound was tested for the rate constant of deacylation against the enzyme Urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University of Illinois

Curated by ChEMBL
LigandPNGBDBM50003742((Lactone1)N-[4-(6-Methylene-2-oxo-tetrahydro-pyran...)
Affinity DataKon:  0.000100M-1s-1Assay Description:Compound was tested for the rate constant of deacylation against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed