BDBM50003806 6-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-3,5-dihydroxy-3-methyl-hexanoic acid ethyl ester::CHEMBL136286

SMILES CCOC(=O)CC(C)(O)CC(O)CSc1nc(c([nH]1)-c1ccccc1)-c1ccccc1

InChI Key InChIKey=RCXLOTKQLBBQSE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50003806   

TargetSterol O-acyltransferase 1(Rattus norvegicus)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003806(6-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-3,5-dihy...)
Affinity DataIC50:  280nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed