BDBM50003817 6-[4,5-Bis-(4-chloro-phenyl)-1H-imidazol-2-ylsulfanyl]-3,5-dihydroxy-3-methyl-hexanoic acid tert-butyl ester::CHEMBL136113

SMILES CC(C)(C)OC(=O)CC(C)(O)CC(O)CSc1nc(c([nH]1)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1

InChI Key InChIKey=NBXPHAJLSVOZCP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50003817   

TargetSterol O-acyltransferase 1(Rattus norvegicus)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003817(6-[4,5-Bis-(4-chloro-phenyl)-1H-imidazol-2-ylsulfa...)
Affinity DataIC50:  250nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed