BDBM50004178 Nociceptin::Nociceptin/orphanin FQ::ORPHANIN FQ

SMILES CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccccc1)[C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(O)=O

InChI Key InChIKey=PULGYDLMFSFVBL-SMFNREODSA-N

Data  23 KI  4 IC50  1 Kd  15 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50004178   

TargetNociceptin receptor(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50004178(Nociceptin | Nociceptin/orphanin FQ | ORPHANIN FQ)
Affinity DataIC50:  0.650nMAssay Description:Displacement of [3H]]nociceptin from human ORL1 receptor expressed in African green monkey COS7 cells after 90 mins by topcount analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50004178(Nociceptin | Nociceptin/orphanin FQ | ORPHANIN FQ)
Affinity DataIC50:  1.80nMAssay Description:Displacement of [3H]]isoVa-RYYRIK-NH2 from human ORL1 receptor low affinity binding site expressed in African green monkey COS7 cells after 90 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50004178(Nociceptin | Nociceptin/orphanin FQ | ORPHANIN FQ)
Affinity DataKd:  0.190nMAssay Description:Binding affinity to human ORL1 receptor expressed in African green monkey COS7 cells assessed per mg protein after 90 mins by Scatchard plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50004178(Nociceptin | Nociceptin/orphanin FQ | ORPHANIN FQ)
Affinity DataIC50:  0.0840nMAssay Description:Binding affinity to human ORL1 receptor expressed in African green monkey COS7 cells assessed per mg protein after 90 mins by Scatchard plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed