BDBM50004423 CHEMBL3238168

SMILES Cc1n[nH]c2ccc(cc12)-c1cncc(n1)N1CCCNCC1

InChI Key InChIKey=FWLLRTWYRORQAU-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50004423   

TargetRho-associated protein kinase 1(Homo sapiens (Human))
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50004423(CHEMBL3238168)
Affinity DataIC50:  140nMAssay Description:Inhibition of truncated ROCK-1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50004423(CHEMBL3238168)
Affinity DataEC50:  380nMAssay Description:Inhibition of ROCK-2 in human GTM3 cells measured up to 2 days by cell impedance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50004423(CHEMBL3238168)
Affinity DataIC50:  36nMAssay Description:Inhibition of truncated ROCK-2 (unknown origin) after 60 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed