BDBM50004572 8-Cyclopentyl-7-methyl-1,3-dipropyl-3,7-dihydro-purine-2,6-dione::CHEMBL22099

SMILES CCCn1c2nc(C3CCCC3)n(C)c2c(=O)n(CCC)c1=O

InChI Key InChIKey=IEKYXRLUXURDTP-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50004572   

TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM50004572(8-Cyclopentyl-7-methyl-1,3-dipropyl-3,7-dihydro-pu...)
Affinity DataKi:  220nMAssay Description:Inhibition of the stimulation by 5'-(N-ethylcarbamoyl) adenosine of adenyl cyclase via adenosine A2 receptor in human platelet membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50004572(8-Cyclopentyl-7-methyl-1,3-dipropyl-3,7-dihydro-pu...)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of (R)-N6-([3H]-phenylisopropyl) adenosine binding to adenosine A1 receptor from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50004572(8-Cyclopentyl-7-methyl-1,3-dipropyl-3,7-dihydro-pu...)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of 1 nM [3H]- N6-(phenylisopropyl) adenosine binding to Adenosine A1 receptor in rat cerebral cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50004572(8-Cyclopentyl-7-methyl-1,3-dipropyl-3,7-dihydro-pu...)
Affinity DataKi:  3.90E+3nMAssay Description:Binding affinity against adenosine A1 receptor in guinea pig forebrain membranes using N6-[3H]cyclohexyladenosine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50004572(8-Cyclopentyl-7-methyl-1,3-dipropyl-3,7-dihydro-pu...)
Affinity DataKi:  8.10E+3nMAssay Description:Binding affinity against adenosine A1 receptor from guinea pig forebrain membranes, using N6-[3H]-cyclohexyladenosine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50004572(8-Cyclopentyl-7-methyl-1,3-dipropyl-3,7-dihydro-pu...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity against adenosine A2 receptor in rat striatal membranes using N-[3H]-ethyladenosin-5''-uronamide as radioligand in the presence of 5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50004572(8-Cyclopentyl-7-methyl-1,3-dipropyl-3,7-dihydro-pu...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity against adenosine A2 receptor from rat striatal membranes, using N-[3H]-ethyladenosin-5''-uronamide as radioligand (in the presence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed