BDBM50005480 (-)-combretastatin::(Z)-3'-hydroxy-3,4,4',5-tetramethoxystilbene::(Z)-5-(3,4,5-trimethoxystyryl)-2-methoxyphenol::(combretastatin A-4)2-Methoxy-5-[2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenol::(combretastin A-4)2-Methoxy-5-[2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenol::2-Methoxy-5-[(Z)-2-(3,4,5-trimethox y-phenyl)-vinyl]-phenol::2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenol::2-Methoxy-5-[2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenol::2-methoxy-5-(3,4,5-trimethoxystyryl)phenol::2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)vinyl]phenol::5-(3,4,5-trimethoxystyryl)-2-methoxyphenol::5-[(S)-2-Hydroxy-2-(3,4,5-trimethoxy-phenyl)-ethyl]-2-methoxy-phenol::CHEMBL67::Combrestatin A-4::Combrestatin A4::Combretastastin A-4::Combretastatin::Combretastatin-A4::Combretastin A-4::Z-Combretastatin A-4::combretastatin A-4, (CSA4)::combretastin A4

SMILES COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1O

InChI Key InChIKey=HVXBOLULGPECHP-WAYWQWQTSA-N

Data  2 KI  102 IC50  2 Kd

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50005480   

TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50005480((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory concentration required against MAP-rich tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed