BDBM50005634 CHEMBL3235375

SMILES CCCCOc1cc(OCCCN(CC)CC)ccc1NC(=O)c1cc(nn1C)-c1ccc(Oc2ccc(F)cc2)cc1

InChI Key InChIKey=HRRAPMWPLALIBT-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50005634   

TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University

Curated by ChEMBL
LigandPNGBDBM50005634(CHEMBL3235375)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of biotinylated human RAGE assessed as bound amyloid beta level after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University

Curated by ChEMBL
LigandPNGBDBM50005634(CHEMBL3235375)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of amyloid beta binding to biotin-labeled human RAGE domain V after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdvanced glycosylation end product-specific receptor(Homo sapiens (Human))
Woosuk University

Curated by ChEMBL
LigandPNGBDBM50005634(CHEMBL3235375)
Affinity DataKd:  4.30E+4nMAssay Description:Binding affinity to biotinylated human RAGE by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed