BDBM50006222 (1S,2R,5R)-5-(6-Amino-purin-9-yl)-3-hydroxymethyl-cyclopent-3-ene-1,2-diol::(neplanocinA)5-(6-Amino-purin-9-yl)-3-hydroxymethyl-cyclopent-3-ene-1,2-diol::5-(6-Amino-purin-9-yl)-3-hydroxymethyl-cyclopent-3-ene-1,2-diol::5-(6-Amino-purin-9-yl)-3-hydroxymethyl-cyclopent-3-ene-1,2-diol (Neplanocin A)::5-(6-Amino-purin-9-yl)-3-hydroxymethyl-cyclopent-3-ene-1,2-diol (Neplonocin A)::5-(6-Amino-purin-9-yl)-3-hydroxymethyl-cyclopent-3-ene-1,2-diol(NP-A)::5-(6-Amino-purin-9-yl)-3-hydroxymethyl-cyclopent-3-ene-1,2-diol(NPA)::5-(6-Amino-purin-9-yl)-3-hydroxymethyl-cyclopent-3-ene-1,2-diol(neplanocin A)::CHEMBL8771::Neplanocin A

SMILES Nc1ncnc2n(cnc12)[C@@H]1C=C(CO)[C@@H](O)[C@H]1O

InChI Key InChIKey=XUGWUUDOWNZAGW-VDAHYXPESA-N

Data  5 KI  10 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50006222   

TargetAdenosylhomocysteinase(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50006222((1S,2R,5R)-5-(6-Amino-purin-9-yl)-3-hydroxymethyl-...)
Affinity DataIC50:  890nMAssay Description:In vitro inhibitory activity of the compound against recombinant S-adenosyl-L-homocysteine hydrolase obtained from human placentaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteinase(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50006222((1S,2R,5R)-5-(6-Amino-purin-9-yl)-3-hydroxymethyl-...)
Affinity DataIC50:  870nMAssay Description:Inhibition of human placental AdoHcy hydrolase expressed in Escherichia coli JM109More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed