BDBM50006429 CHEMBL302984::{1-[1-{1-Cyclohexylmethyl-2-hydroxy-3-[4-(2-pyridin-4-yl-ethyl)-5-trifluoromethyl-4H-[1,2,4]triazol-3-ylsulfanyl]-propylcarbamoyl}-2-(1H-imidazol-4-yl)-ethylcarbamoyl]-2-phenyl-ethyl}-carbamic acid tert-butyl ester; hydrate

SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)CSc1nnc(n1CCc1ccncc1)C(F)(F)F

InChI Key InChIKey=JMNQPINYSFYFQQ-YRCZKMHPSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50006429   

TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006429(CHEMBL302984 | {1-[1-{1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  41nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed