BDBM50006464 CHEMBL303210::[4-Methyl-6-oxo-1-(5-trifluoromethyl-benzothiazol-2-ylmethyl)-1,6-dihydro-pyridazin-3-yl]-acetic acid

SMILES Cc1cc(=O)n(Cc2nc3cc(ccc3s2)C(F)(F)F)nc1CC(O)=O

InChI Key InChIKey=RNDNMIOYEBTJDS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50006464   

TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006464(CHEMBL303210 | [4-Methyl-6-oxo-1-(5-trifluoromethy...)
Affinity DataIC50:  18nMAssay Description:Inhibitory activity against aldose reductase isolated from human placentaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed