BDBM50006479 CHEMBL69371::[7-(4-Bromo-2-fluoro-benzyl)-8-oxo-7,8-dihydro-pyrido[2,3-d]pyridazin-5-yl]-acetic acid

SMILES OC(=O)Cc1nn(Cc2ccc(Br)cc2F)c(=O)c2ncccc12

InChI Key InChIKey=XFFKMUMASJSILS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50006479   

TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006479(CHEMBL69371 | [7-(4-Bromo-2-fluoro-benzyl)-8-oxo-7...)
Affinity DataIC50:  760nMAssay Description:Inhibitory activity against aldose reductase isolated from human placentaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed