BDBM50006742 CHEMBL3236553

SMILES Nc1nc(cc(n1)N1CCNCC1)C1CCCC1

InChI Key InChIKey=UYXWQSZIUMRFIW-UHFFFAOYSA-N

Data  4 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50006742   

TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50006742(CHEMBL3236553)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]histamine from human recombinant histamine H4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50006742(CHEMBL3236553)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]histamine from human recombinant histamine H4 receptor expressed in SK-N-MC cells after 45 mins by competition binding analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Mus musculus (mouse))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50006742(CHEMBL3236553)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]histamine from mouse histamine H4 receptor expressed in SK-N-MC cells after 45 mins by competition binding analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50006742(CHEMBL3236553)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in SK-N-MC cells after 45 mins by competition bind...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Mus musculus (mouse))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50006742(CHEMBL3236553)
Affinity DataEC50:  7.30nMAssay Description:Partial agonist activity at mouse histamine H4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50006742(CHEMBL3236553)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human H4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed