BDBM50006875 CHEMBL263969::N-{(S)-2-[(R)-2-(Adamantan-2-yloxycarbonylamino)-3-(1H-indol-3-yl)-2-methyl-propionylamino]-1-phenyl-ethyl}-succinamic acid::N-{2-[2-(Adamantan-2-yloxycarbonylamino)-3-(1H-indol-3-yl)-2-methyl-propionylamino]-1-phenyl-ethyl}-succinamic acid::PD-136621

SMILES CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1C2CC3CC(C2)CC1C3)C(=O)NC[C@@H](NC(=O)CCC(O)=O)c1ccccc1

InChI Key InChIKey=FVQSSYMRZKLFDR-QTZXECCPSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50006875   

TargetCholecystokinin receptor type A(RAT)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50006875(CHEMBL263969 | N-{(S)-2-[(R)-2-(Adamantan-2-yloxyc...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of [3H]-propionyl-CCK-8 binding to rat pancreas cholecystokinin-A (CCK-A) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(MOUSE)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50006875(CHEMBL263969 | N-{(S)-2-[(R)-2-(Adamantan-2-yloxyc...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of [3H]-propionyl-CCK-8 binding to mouse cerebral cortex membrane cholecystokinin-B (CCK-B) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(MOUSE)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50006875(CHEMBL263969 | N-{(S)-2-[(R)-2-(Adamantan-2-yloxyc...)
Affinity DataIC50:  43nMAssay Description:Inhibition of [125I]-CCK-8 to Cholecystokinin type B receptor in the mouse cerebral cortex.More data for this Ligand-Target Pair
In DepthDetails Article
TargetCholecystokinin receptor type A(RAT)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50006875(CHEMBL263969 | N-{(S)-2-[(R)-2-(Adamantan-2-yloxyc...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibitory concentration against radioligand [125I]Bolton-Hunter labeled CCK-8 to cholecystokinin type A receptor in the rat pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(MOUSE)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50006875(CHEMBL263969 | N-{(S)-2-[(R)-2-(Adamantan-2-yloxyc...)
Affinity DataIC50:  1.70nMAssay Description:Evaluated for inhibition of cholecystokinin type B receptor by displacing [125I]-Bolton hunter CCK-8 radioligand in the mouse cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50006875(CHEMBL263969 | N-{(S)-2-[(R)-2-(Adamantan-2-yloxyc...)
Affinity DataIC50:  4.50E+3nMAssay Description:Evaluated for inhibition of cholecystokinin type A receptor by displacing [125I]bolton hunter CCK-8 radioligand in the rat pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(MOUSE)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50006875(CHEMBL263969 | N-{(S)-2-[(R)-2-(Adamantan-2-yloxyc...)
Affinity DataIC50:  43nMAssay Description:Inhibitory concentration against radioligand [125I]Bolton-Hunter labeled CCK-8 to cholecystokinin type B receptor in the mouse cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50006875(CHEMBL263969 | N-{(S)-2-[(R)-2-(Adamantan-2-yloxyc...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of [125I]-CCK-8 binding to Cholecystokinin type A receptor of rat pancreasMore data for this Ligand-Target Pair
In DepthDetails Article