BDBM50006875 CHEMBL263969::N-{(S)-2-[(R)-2-(Adamantan-2-yloxycarbonylamino)-3-(1H-indol-3-yl)-2-methyl-propionylamino]-1-phenyl-ethyl}-succinamic acid::N-{2-[2-(Adamantan-2-yloxycarbonylamino)-3-(1H-indol-3-yl)-2-methyl-propionylamino]-1-phenyl-ethyl}-succinamic acid::PD-136621
SMILES CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1C2CC3CC(C2)CC1C3)C(=O)NC[C@@H](NC(=O)CCC(O)=O)c1ccccc1
InChI Key InChIKey=FVQSSYMRZKLFDR-QTZXECCPSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50006875
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of [3H]-propionyl-CCK-8 binding to rat pancreas cholecystokinin-A (CCK-A) receptorMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(MOUSE)
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of [3H]-propionyl-CCK-8 binding to mouse cerebral cortex membrane cholecystokinin-B (CCK-B) receptorMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(MOUSE)
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of [125I]-CCK-8 to Cholecystokinin type B receptor in the mouse cerebral cortex.More data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibitory concentration against radioligand [125I]Bolton-Hunter labeled CCK-8 to cholecystokinin type A receptor in the rat pancreasMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(MOUSE)
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Evaluated for inhibition of cholecystokinin type B receptor by displacing [125I]-Bolton hunter CCK-8 radioligand in the mouse cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+3nMAssay Description:Evaluated for inhibition of cholecystokinin type A receptor by displacing [125I]bolton hunter CCK-8 radioligand in the rat pancreasMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(MOUSE)
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibitory concentration against radioligand [125I]Bolton-Hunter labeled CCK-8 to cholecystokinin type B receptor in the mouse cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of [125I]-CCK-8 binding to Cholecystokinin type A receptor of rat pancreasMore data for this Ligand-Target Pair