BDBM50006946 2-[2-(2-{2-[2-Diallylamino-3-(4-hydroxy-phenyl)-propionylamino]-2-methyl-propionylamino}-2-methyl-propionylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::CHEMBL47545::ICI-174864
SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)C(C)(C)NC(=O)C(C)(C)NC(=O)[C@H](Cc1ccc(O)cc1)N(CC=C)CC=C)C(O)=O
InChI Key InChIKey=XUWLAGNFLUARAN-CHQNGUEUSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 17 hits for monomerid = 50006946
Affinity DataKi: 19nMAssay Description:Binding affinity towards opioid receptor delta 1 expressed in CHO cells was determined by using [3H]DPDPE as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Binding affinity was measured by the displacement of [3H]- EK in guinea pig brain membrane of opioid receptor kappaMore data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:The compound was evaluated for binding affinity against Opioid receptor delta 1 in guinea pig brain membrane using [3H]- DPDPE as ligandMore data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Compound was evaluated for binding affinity at Opioid receptor delta 1 in guinea pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Binding affinity was measured by the displacement of [3H]- DADLE in guinea pig brain membrane of opioid receptor deltaMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:The compound was evaluated for binding affinity against opioid receptor mu in guinea pig brain membranes using [3H]- DAMGO as ligandMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity was measured by the displacement of [3H]- EK in guinea pig brain membrane of Opioid receptor kappa 1More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity was measured by the displacement of [3H]- DAMGO in guinea pig brain membrane of opioid receptor muMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:The compound was evaluated for binding affinity against the opioid receptor kappa in guinea pig brain membranes using [3H]- U-69,593More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Compound was evaluated for binding affinity of Opioid receptor kappa 1 in guinea pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Compound was evaluated for binding affinity at Opioid receptor mu 1 in guinea pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity was measured by the displacement of [3H]- DAMGO in guinea pig brain membrane of Opioid receptor mu 1More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity was measured by the displacement of [3H]- EK in guinea pig brain membrane of Opioid receptor kappa 1More data for this Ligand-Target Pair
Affinity DataIC50: 1.89E+4nMAssay Description:Binding affinity was measured in cloned Opioid receptor mu 1 expressed in CHO cells using [3H]- DAMGO as radioligand.More data for this Ligand-Target Pair
Affinity DataIC50: 703nMAssay Description:Binding affinity was measured in cloned Opioid receptor delta 1 expressed in CHO cells using [3H]- DPDPE as radioligand.More data for this Ligand-Target Pair
Affinity DataEC50: 116nMAssay Description:Inverse agonist activity at human DOR expressed in CHO cell membranes by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.25E+3nMAssay Description:Tested for agonist activity against delta opioid receptor mouse vas deferensMore data for this Ligand-Target Pair