BDBM50007285 CHEMBL317142::Sodium; 6-{3-[bis-(4-fluoro-phenyl)-methyl]-1-isopropyl-naphthalen-2-yloxy}-3,5-dihydroxy-hexanoate
SMILES CC(C)c1c(OCC(O)C[C@@H](O)CC([O-])=O)c(cc2ccccc12)C(c1ccc(F)cc1)c1ccc(F)cc1
InChI Key InChIKey=KMUHRPGZKRKKCZ-DCWQJPKNSA-M
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50007285
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Hoechst
Curated by ChEMBL
Hoechst
Curated by ChEMBL
Affinity DataIC50: 380nMAssay Description:In vitro inhibition of HMG-CoA reductase in solubilized rat liver.More data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of the incorporation of sodium [14C]acetate into cholesterol in HEP G2 cells.More data for this Ligand-Target Pair