BDBM50008072 (+)-pilocarpine::(3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydrofuran-2(3H)-one::(3S,4R)-3-ethyldihydro-4-((1-methyl-1H-imidazol-5-yl)methyl)-2(3H)-furanone::(3S-cis)-3-ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-2(3H)-furanone::CHEMBL550::ISOPTO CARPINE::PILOCARPINE::PILOCARPINE HYDROCHLORIDE

SMILES CC[C@H]1[C@@H](Cc2cncn2C)COC1=O

InChI Key InChIKey=QCHFTSOMWOSFHM-WPRPVWTQSA-N

Data  18 KI  7 IC50  4 Kd  5 EC50

PDB links: 4 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50008072   

LigandPNGBDBM50008072((+)-pilocarpine | (3S,4R)-3-ethyl-4-[(1-methyl-1H-...)
Affinity DataKi:  3.10E+3nMAssay Description:Compound was evaluated for its affinity towards Muscarinic acetylcholine receptor M1, using [3H]- pirenzepine, a radioligand displacement assay in ra...More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50008072((+)-pilocarpine | (3S,4R)-3-ethyl-4-[(1-methyl-1H-...)
Affinity DataKi:  7.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50008072((+)-pilocarpine | (3S,4R)-3-ethyl-4-[(1-methyl-1H-...)
Affinity DataKi:  9.80E+3nMAssay Description:Compound was evaluated for its affinity towards Muscarinic acetylcholine receptor M2, using [3H]- N-methyl-scopolamine, a radioligand displacement as...More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50008072((+)-pilocarpine | (3S,4R)-3-ethyl-4-[(1-methyl-1H-...)
Affinity DataIC50:  4.43E+3nMAssay Description:Compound was evaluated for the displacement of the muscarinic QNB in a genetically transformed rat cell line (m1c2) transfected with cloned m1 recept...More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50008072((+)-pilocarpine | (3S,4R)-3-ethyl-4-[(1-methyl-1H-...)
Affinity DataIC50:  8.80E+3nMAssay Description:Compound was evaluated for the displacement of the muscarinic QNB in rat heart homogenate containing the pharmacologic M2 receptor (M2-QNB heart)More data for this Ligand-Target Pair
In DepthDetails Article