BDBM50008440 CHEMBL143863::{3-[(3,5-Difluoro-2-hydroxy-phenylcarbamoyl)-methyl]-4-oxo-3,4-dihydro-phthalazin-1-yl}-acetic acid

SMILES OC(=O)Cc1nn(CC(=O)Nc2cc(F)cc(F)c2O)c(=O)c2ccccc12

InChI Key InChIKey=XANFACVRDLABMV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50008440   

TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50008440(CHEMBL143863 | {3-[(3,5-Difluoro-2-hydroxy-phenylc...)
Affinity DataIC50:  170nMAssay Description:In vitro inhibitory activity against aldose reductase isolated from human placentaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed