BDBM50008705 CHEMBL168418::N-Benzyl-2-phenoxy-nicotinamide

SMILES O=C(NCc1ccccc1)c1cccnc1Oc1ccccc1

InChI Key InChIKey=WKEHRSGEQPYYPS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50008705   

TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50008705(CHEMBL168418 | N-Benzyl-2-phenoxy-nicotinamide)
Affinity DataIC50:  3.16E+3nMAssay Description:Negative log of inhibitiory concentration determined against c-Jun N-terminal kinase (Activity reported against the isolated JNK-1 enzyme)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50008705(CHEMBL168418 | N-Benzyl-2-phenoxy-nicotinamide)
Affinity DataIC50:  4.90E+4nMAssay Description:Inhibition of [3H]rolipram binding to rat brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50008705(CHEMBL168418 | N-Benzyl-2-phenoxy-nicotinamide)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of [3H]cAMP (NEN NET-275) binding to Calcium-Independent Phosphodiesterase from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed