BDBM50008976 CHEMBL137742::[2-Methyl-8-((E)-3-phenyl-propenyl)-imidazo[1,2-a]pyridin-3-yl]-acetonitrile::[2-Methyl-8-(3-phenyl-propenyl)-imidazo[1,2-a]pyridin-3-yl]-acetonitrile

SMILES Cc1nc2c(\C=C\Cc3ccccc3)cccn2c1CC#N

InChI Key InChIKey=UAVXOYOVPGTUTA-BJMVGYQFSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50008976   

TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50008976(CHEMBL137742 | [2-Methyl-8-((E)-3-phenyl-propenyl)...)
Affinity DataIC50:  1.40E+4nMpH: 7.4Assay Description:Inhibition of purified H+/K+ ATPase at pH 7.4 as released inorganic phosphate from ATP using hog stomach gastric membrane vesiclesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50008976(CHEMBL137742 | [2-Methyl-8-((E)-3-phenyl-propenyl)...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of H+/K+ ATPase as reduced acid formation in rabbit gastric glandsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed