BDBM50009454 CHEMBL3234136

SMILES CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H](CCCC[N+](C)(C)C)C(=O)N[C@@H](CO)C(N)=O

InChI Key InChIKey=PWTPHMJTGGEKCZ-SJSXQSQASA-O

Data  2 IC50  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50009454   

TargetChromobox protein homolog 7(Homo sapiens (Human))
University Of Victoria

Curated by ChEMBL
LigandPNGBDBM50009454(CHEMBL3234136)
Affinity DataIC50:  1.10E+4nMAssay Description:Displacement of FITC-labeled H3K27me3 from CBX7 (unknown origin) after 15 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChromobox protein homolog 7(Homo sapiens (Human))
University Of Victoria

Curated by ChEMBL
LigandPNGBDBM50009454(CHEMBL3234136)
Affinity DataKd:  2.00E+3nMAssay Description:Binding affinity to CBX7 (unknown origin) by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChromobox protein homolog 7(Homo sapiens (Human))
University Of Victoria

Curated by ChEMBL
LigandPNGBDBM50009454(CHEMBL3234136)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of N terminally fluorescein-tagged H3K27me3 binding to N terminallyHis6-tagged human Cbx7 expressed in Escherichia coli BL21 (DE3) by fluo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 SUMO-protein ligase CBX4(Homo sapiens (Human))
University Of Victoria

Curated by ChEMBL
LigandPNGBDBM50009454(CHEMBL3234136)
Affinity DataKd:  3.70E+3nMAssay Description:Binding affinity to CBX4 (unknown origin) by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChromobox protein homolog 1(Homo sapiens (Human))
University Of Victoria

Curated by ChEMBL
LigandPNGBDBM50009454(CHEMBL3234136)
Affinity DataKd:  4.30E+4nMAssay Description:Binding affinity to CBX1 (unknown origin) by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChromobox protein homolog 8(Homo sapiens (Human))
University Of Victoria

Curated by ChEMBL
LigandPNGBDBM50009454(CHEMBL3234136)
Affinity DataKd:  1.42E+4nMAssay Description:Binding affinity to CBX8 (unknown origin) by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed