BDBM50009672 AdoHcy::CHEMBL418052::S-(5'-adenosyl)-L-homocysteine::S-(5'-deoxyadenosin-5'-yl)-L-homocysteine::S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-ribofuranos-5-yl]-L-homocysteine::S-adenosyl-L-homocysteine::SAH::US8895245, S-Adenosyl-L-homocysteine (SAH)::US9175331, 1::US9333217, S-Adenosyl-L-homocysteine (SAH)

SMILES N[C@@H](CCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(O)=O

InChI Key InChIKey=ZJUKTBDSGOFHSH-WFMPWKQPSA-N

Data  17 KI  75 IC50  6 Kd

PDB links: 1202 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50009672   

TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM50009672(AdoHcy | CHEMBL418052 | S-(5'-adenosyl)-L-homocyst...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human recombinant DNMT1 expressed in baculovirus-insect cell system by scintillation countingMore data for this Ligand-Target Pair
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Deutsches Krebsforschungszentrum

Curated by ChEMBL
LigandPNGBDBM50009672(AdoHcy | CHEMBL418052 | S-(5'-adenosyl)-L-homocyst...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human recombinant DNMT3B expressed in baculovirus-insect cell system by scintillation countingMore data for this Ligand-Target Pair