BDBM50010054 1-{1-[3-(1,1-Dioxo-1H-1lambda*6*-naphtho[1,8-cd]isothiazol-2-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::CHEMBL81813
SMILES O=c1[nH]c2ccccc2n1C1CCN(CCCN2c3cccc4cccc(c34)S2(=O)=O)CC1
InChI Key InChIKey=ZXYZYKRBNAHRIG-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50010054
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
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Curated by ChEMBL
Centre De Recherches De Vitry Alfortville Rh£Ne-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:The concentration required to inhibit [3H]spiperone binding to dopamine receptor D2 in rat brain membranes (in vitro)More data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
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Curated by ChEMBL
Centre De Recherches De Vitry Alfortville Rh£Ne-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:The concentration required to inhibit [3H]prazosin binding to Alpha-1 adrenergic receptor in rat brain membranes was measured (in vitro)More data for this Ligand-Target Pair
TargetSerotonin 2 (5-HT2) receptor(RAT)
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Curated by ChEMBL
Centre De Recherches De Vitry Alfortville Rh£Ne-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:The concentration required to inhibit [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor in rat brain membranes (in vitro)More data for this Ligand-Target Pair