BDBM50011694 CHEMBL354360::{1-[1-[2-(5-Benzyloxymethyl-1-methyl-2-oxo-pyrrolidin-3-yl)-1-cyclohexylmethyl-2-hydroxy-ethylcarbamoyl]-2-(1H-imidazol-4-yl)-ethylcarbamoyl]-2-phenyl-ethyl}-carbamic acid tert-butyl ester

SMILES CN1[C@H](COCc2ccccc2)C[C@@H]([C@H](O)[C@H](CC2CCCCC2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](Cc2ccccc2)NC(=O)OC(C)(C)C)C1=O

InChI Key InChIKey=UVZNGTDEZCYVKR-DUGSHLAESA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50011694   

TargetPepsin A(Porcine)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011694(CHEMBL354360 | {1-[1-[2-(5-Benzyloxymethyl-1-methy...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory concentration against PepsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011694(CHEMBL354360 | {1-[1-[2-(5-Benzyloxymethyl-1-methy...)
Affinity DataIC50:  4.40E+3nMpH: 7.4Assay Description:In vitro renin inhibition was measured at pH 7.4 by using human plasma renin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastricsin(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011694(CHEMBL354360 | {1-[1-[2-(5-Benzyloxymethyl-1-methy...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory concentration against GastricsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011694(CHEMBL354360 | {1-[1-[2-(5-Benzyloxymethyl-1-methy...)
Affinity DataIC50:  115nMAssay Description:Inhibitory concentration against cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed