BDBM50011700 Acetic acid 4-{2-[2-(2-tert-butoxycarbonylamino-3-phenyl-propionylamino)-3-(1H-imidazol-4-yl)-propionylamino]-3-cyclohexyl-1-hydroxy-propyl}-1-methyl-5-oxo-pyrrolidin-2-ylmethyl ester::CHEMBL170289

SMILES CN1[C@H](COC(C)=O)C[C@@H]([C@H](O)[C@H](CC2CCCCC2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](Cc2ccccc2)NC(=O)OC(C)(C)C)C1=O

InChI Key InChIKey=HGHJCVYAXOEPSB-JNRWAQIZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50011700   

TargetRenin(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011700(Acetic acid 4-{2-[2-(2-tert-butoxycarbonylamino-3-...)
Affinity DataIC50:  155nMpH: 7.4Assay Description:In vitro renin inhibition was measured at pH 7.4 by using purified human kidney renin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011700(Acetic acid 4-{2-[2-(2-tert-butoxycarbonylamino-3-...)
Affinity DataIC50:  157nMpH: 7.4Assay Description:In vitro renin inhibition was measured at pH 7.4 by using human plasma renin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed