BDBM50011762 (1R,5S)1-(4-Amino-phenyl)-3-cyclohexylmethyl-3-aza-bicyclo[3.1.0]hexane-2,4-dione::(1S,5R)1-(4-Amino-phenyl)-3-cyclohexylmethyl-3-aza-bicyclo[3.1.0]hexane-2,4-dione::1-(4-Amino-phenyl)-3-cyclohexylmethyl-3-aza-bicyclo[3.1.0]hexane-2,4-dione::CHEMBL281947

SMILES Nc1ccc(cc1)C12CC1C(=O)N(CC1CCCCC1)C2=O

InChI Key InChIKey=WUHIUYRMTKSZGJ-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50011762   

TargetAromatase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50011762((1R,5S)1-(4-Amino-phenyl)-3-cyclohexylmethyl-3-aza...)
Affinity DataIC50:  230nMAssay Description:In vitro inhibition of progesterone production in hamster ovarian tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50011762((1R,5S)1-(4-Amino-phenyl)-3-cyclohexylmethyl-3-aza...)
Affinity DataIC50:  780nMAssay Description:In vitro inhibition of human placental Cytochrome P450 19A aromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50011762((1R,5S)1-(4-Amino-phenyl)-3-cyclohexylmethyl-3-aza...)
Affinity DataIC50: >3.30E+5nMAssay Description:In vitro inhibition of estrogen production in hamster ovarian tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50011762((1R,5S)1-(4-Amino-phenyl)-3-cyclohexylmethyl-3-aza...)
Affinity DataIC50:  5nMAssay Description:In vitro inhibition of cytochrome P450 19A1 AromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50011762((1R,5S)1-(4-Amino-phenyl)-3-cyclohexylmethyl-3-aza...)
Affinity DataIC50: >3.40E+4nMAssay Description:In vitro inhibition of aldosterone production in rat adrenal tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50011762((1R,5S)1-(4-Amino-phenyl)-3-cyclohexylmethyl-3-aza...)
Affinity DataIC50:  12nMAssay Description:In vitro inhibition of estrogen production in hamster ovarian tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50011762((1R,5S)1-(4-Amino-phenyl)-3-cyclohexylmethyl-3-aza...)
Affinity DataIC50: >3.30E+5nMAssay Description:In vitro inhibition of progesterone production in hamster ovarian tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50011762((1R,5S)1-(4-Amino-phenyl)-3-cyclohexylmethyl-3-aza...)
Affinity DataIC50:  5nMAssay Description:In vitro inhibition of cytochrome P450 19A1 AromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50011762((1R,5S)1-(4-Amino-phenyl)-3-cyclohexylmethyl-3-aza...)
Affinity DataIC50: >3.40E+4nMAssay Description:In vitro inhibition of estrogen production in hamster ovarian tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed