BDBM50012154 (3S,8R)-3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::CHEMBL21112

SMILES COC(=O)C1C2CCC(C[C@@H]1c1ccc(F)cc1)N2

InChI Key InChIKey=HQXXRDHSJOKBAP-DBBXXEFVSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50012154   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Biochemicals

Curated by ChEMBL
LigandPNGBDBM50012154((3S,8R)-3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]oc...)
Affinity DataIC50:  36nMAssay Description:Compound was evaluated for inhibition of specifically bound [3H]- cocaine (2.7 nM) against Dopamine transporter in cynomolgus monkeysMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Biochemicals

Curated by ChEMBL
LigandPNGBDBM50012154((3S,8R)-3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]oc...)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50012154((3S,8R)-3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]oc...)
Affinity DataIC50:  19nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50012154((3S,8R)-3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]oc...)
Affinity DataIC50:  69nMAssay Description:Inhibition of [3H]paroxetine binding to 5-hydroxytryptamine (5-HT) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed