BDBM50012640 CHEMBL2403779
SMILES [H][C@@]12C[C@@]1(N=C(N)COC2)c1cc(NC(=O)c2ccc(Cl)cn2)ccc1F
InChI Key InChIKey=HOPLUAKMYRGQPD-YPMLDQLKSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50012640
Affinity DataIC50: 73nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing APP695 assessed as inhibition of amyloid beta (1 to 40) production after 18 to 20 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of BACE2 in rat INS-1E cells assessed as TMEM27 cleavage preincubated for 2 hrs followed by doxycycline addition measured after 46 hrs by ...More data for this Ligand-Target Pair