BDBM50012937 CHEMBL76697::Less polar Epimer-6-Cyclohexyl-4-hydroxy-2-isopropyl-5-[2-(8-propyl-6-pyridin-3-yl-[1,2,4]triazolo[4,3-a]pyrazin-3-yl)-3-pyridin-3-yl-propionylamino]-hexanoic acid (2-dimethylamino-ethyl)-amide::More polar Epimer-6-Cyclohexyl-4-hydroxy-2-isopropyl-5-[2-(8-propyl-6-pyridin-3-yl-[1,2,4]triazolo[4,3-a]pyrazin-3-yl)-3-pyridin-3-yl-propionylamino]-hexanoic acid (2-dimethylamino-ethyl)-amide

SMILES CCCc1nc(cn2c(nnc12)C(Cc1cccnc1)C(=O)NC(CC1CCCCC1)C(O)CC(C(C)C)C(=O)NCCN(C)C)-c1cccnc1

InChI Key InChIKey=AYLQFSBXZTZHLQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50012937   

TargetRenin(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012937(CHEMBL76697 | Less polar Epimer-6-Cyclohexyl-4-hyd...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012937(CHEMBL76697 | Less polar Epimer-6-Cyclohexyl-4-hyd...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed