BDBM50014079 (R)-2-Benzyl-N*1*-[(S)-1-[(1S,2R)-1-cyclohexylmethyl-2-((S)-3-ethyl-2-oxo-oxazolidin-5-yl)-2-hydroxy-ethylcarbamoyl]-2-(3H-imidazol-4-yl)-ethyl]-N*4*-(2-hydroxy-ethyl)-N*4*-methyl-succinamide::CHEMBL61420

SMILES CCN1C[C@H](OC1=O)[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](CC(=O)N(C)CCO)Cc1ccccc1

InChI Key InChIKey=XRWIXYJMRXSNIB-GXPIJPPGSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50014079   

TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014079((R)-2-Benzyl-N*1*-[(S)-1-[(1S,2R)-1-cyclohexylmeth...)
Affinity DataIC50:  2.5nMpH: 7.4Assay Description:Inhibitory activity against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014079((R)-2-Benzyl-N*1*-[(S)-1-[(1S,2R)-1-cyclohexylmeth...)
Affinity DataIC50:  0.850nMpH: 6.5Assay Description:Inhibitory activity against purified human renal renin at pH 6.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed