BDBM50014589 CHEMBL3261762

SMILES Cl.CC(C)C[C@H](N)C(=O)NCC(=O)N[C@H]1C[C@H](N(C1)S(=O)(=O)c1ccc(Cl)cc1)C(=O)NO

InChI Key InChIKey=GXSCUJTUGROEHG-GEUPQXMHSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50014589   

TargetAminopeptidase N(Sus scrofa (Pig))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50014589(CHEMBL3261762)
Affinity DataIC50:  7.23E+4nMAssay Description:Inhibition of pig kidney microsomal APN using L-Leu-p-nitroanilide as substrate preincubated for 5 mins before substrate addition measured after 30 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50014589(CHEMBL3261762)
Affinity DataIC50:  270nMAssay Description:Inhibition of MMP2 (unknown origin) using succinylated gelatin as substrate preincubated for 10 mins before substrate addition measured after 30 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50014589(CHEMBL3261762)
Affinity DataIC50:  1.84E+4nMAssay Description:Inhibition of MMP2 in human SKOV3 cell suspension using succinylated gelatin as substrate preincubated for 10 mins before substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed