BDBM50015011 CHEMBL3262363::US9259422, 7a, 2-MePh- BU10101::US9480684, 7a, 2- MePh- BU10101
SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]51CC[C@@]2(OC)[C@]([H])(C1)[C@](C)(O)c1ccccc1C)ccc3O
InChI Key InChIKey=MCJYXNRYAYCDAR-PPMCTTEPSA-N
Data 6 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50015011
Affinity DataKi: 0.160nMAssay Description:Displacement of [3H]diprenorphine from recombinant human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
Affinity DataKi: 0.160nM ΔG°: -13.4kcal/molepH: 7.4 T: 2°CAssay Description:As Alt et al., 2002. Membranes (20 ug) are incubated in 50 mM Tris-HCl,
pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or
presence ...More data for this Ligand-Target Pair
Affinity DataKi: 0.190nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.190nM ΔG°: -13.3kcal/molepH: 7.4 T: 2°CAssay Description:As Alt et al., 2002. Membranes (20 ug) are incubated in 50 mM Tris-HCl,
pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or
presence ...More data for this Ligand-Target Pair
Affinity DataKi: 0.190nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair