BDBM50015752 (8-Chloro-1-ethyl-[1,2,4]triazolo[4,3-a]quinoxalin-4-yl)-isopropyl-amine::CHEMBL72177

SMILES CCc1nnc2c(NC(C)C)nc3ccc(Cl)cc3n12

InChI Key InChIKey=JORCMIACBHYGGJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50015752   

TargetAdenosine receptor A1(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50015752((8-Chloro-1-ethyl-[1,2,4]triazolo[4,3-a]quinoxalin...)
Affinity DataIC50:  60nMAssay Description:Binding affinity towards the adenosine A1 receptor in cerebral cortices of Sprague-Dawley male rats using [3H]CHA as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50015752((8-Chloro-1-ethyl-[1,2,4]triazolo[4,3-a]quinoxalin...)
Affinity DataIC50:  2.00E+3nMAssay Description:Evaluated for Ca++ dependent phosphodiesterase activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50015752((8-Chloro-1-ethyl-[1,2,4]triazolo[4,3-a]quinoxalin...)
Affinity DataIC50:  1.70E+3nMAssay Description:Evaluated for the binding affinity towards the Adenosine A2 receptor in corpora striata of rats using [3H]NECA as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed