BDBM50015983 (S)-3-Ethyl-1-octyl-4,5-dihydro-3H-[3,4']bipyridinyl-2,6-dione::3-Ethyl-1-octyl-4,5-dihydro-3H-[3,4']bipyridinyl-2,6-dione::CHEMBL39661

SMILES CCCCCCCCN1C(=O)CCC(CC)(C1=O)c1ccncc1

InChI Key InChIKey=OORIPAIYDLQOTG-UHFFFAOYSA-N

Data  2 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50015983   

TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50015983((S)-3-Ethyl-1-octyl-4,5-dihydro-3H-[3,4']bipyridin...)
Affinity DataKi:  120nMAssay Description:Inhibition of human placental cytochrome P450 19A1 with testosteroneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50015983((S)-3-Ethyl-1-octyl-4,5-dihydro-3H-[3,4']bipyridin...)
Affinity DataKi:  480nMAssay Description:Inhibition of human placental cytochrome P450 19A1 with androstenedioneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50015983((S)-3-Ethyl-1-octyl-4,5-dihydro-3H-[3,4']bipyridin...)
Affinity DataIC50:  800nMAssay Description:Inhibition of human placental cytochrome P450 19A1 with testosteroneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50015983((S)-3-Ethyl-1-octyl-4,5-dihydro-3H-[3,4']bipyridin...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibitory activity against human placental cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50015983((S)-3-Ethyl-1-octyl-4,5-dihydro-3H-[3,4']bipyridin...)
Affinity DataIC50:  1.10E+5nMAssay Description:Inhibition of bovine desmolase, cytochrome P450 11A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50015983((S)-3-Ethyl-1-octyl-4,5-dihydro-3H-[3,4']bipyridin...)
Affinity DataIC50:  800nMAssay Description:Inhibition of Cytochrome P450 19A1 in human placentaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50015983((S)-3-Ethyl-1-octyl-4,5-dihydro-3H-[3,4']bipyridin...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of aromatase cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails Article