BDBM50016518 CHEMBL3260687

SMILES CCOC(=O)c1c(CSc2ccc(OC(F)(F)F)cc2)n(C)c2ccc(O)cc12

InChI Key InChIKey=DCACUALOKCQKSV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50016518   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Naples

Curated by ChEMBL
LigandPNGBDBM50016518(CHEMBL3260687)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of 5-LO in human polymorphonuclear leukocytes assessed as inhibition of LTB4 production from arachidonic acid preincubated for 15 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Naples

Curated by ChEMBL
LigandPNGBDBM50016518(CHEMBL3260687)
Affinity DataIC50:  900nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 5 to 10 mins by HPLC ana...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed