BDBM50016521 CHEMBL1331577
SMILES CCOC(=O)c1c(CSc2ccccc2)n(C)c2ccc(O)cc12
InChI Key InChIKey=RTIBLQQLUBXQDX-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50016521
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Naples
Curated by ChEMBL
University Of Naples
Curated by ChEMBL
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 5 to 10 mins by HPLC ana...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Naples
Curated by ChEMBL
University Of Naples
Curated by ChEMBL
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of 5-LO in human polymorphonuclear leukocytes assessed as inhibition of LTB4 production from arachidonic acid preincubated for 15 mins by ...More data for this Ligand-Target Pair