BDBM50016986 7-Chloro-2-(4-methoxy-benzyl)-3-methyl-5-propyl-benzofuran-4-ol::CHEMBL17815
SMILES CCCc1cc(Cl)c2oc(Cc3ccc(OC)cc3)c(C)c2c1O
InChI Key InChIKey=PLRQEJPVGOQVSJ-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50016986
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Canada
Curated by ChEMBL
Merck Frosst Canada
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of 5-lipoxygenase reaction catalyzed by purified enzyme from porcine leukocytesMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Canada
Curated by ChEMBL
Merck Frosst Canada
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Concentration required for 50 % inhibition of arachidonic acid oxidation by rat 5-lipoxygenaseMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Merck Frosst Canada
Curated by ChEMBL
Merck Frosst Canada
Curated by ChEMBL
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of partially purified 15-lipoxygenase from human leukocytesMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Canada
Curated by ChEMBL
Merck Frosst Canada
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Concentration required for 50 % inhibition of leukotriene B4 production in human PMN compared with controls in the absence of compoundMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Sus scrofa)
Merck Frosst Canada
Curated by ChEMBL
Merck Frosst Canada
Curated by ChEMBL
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibitory activity of the compound towards porcine 12-lipoxygenaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory activity of the compound towards soybean lipoxygenaseMore data for this Ligand-Target Pair