BDBM50016990 2-(4-Methoxy-benzyl)-3,7-dimethyl-5-propyl-benzofuran-4-ol::CHEMBL18394

SMILES CCCc1cc(C)c2oc(Cc3ccc(OC)cc3)c(C)c2c1O

InChI Key InChIKey=QBJUFUHYFMGSJB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50016990   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50016990(2-(4-Methoxy-benzyl)-3,7-dimethyl-5-propyl-benzofu...)
Affinity DataIC50:  140nMAssay Description:Concentration required for 50 % inhibition of arachidonic acid oxidation by rat 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50016990(2-(4-Methoxy-benzyl)-3,7-dimethyl-5-propyl-benzofu...)
Affinity DataIC50:  12nMAssay Description:Concentration required for 50 % inhibition of leukotriene B4 production in human PMN compared with controls in the absence of compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed