BDBM50017045 8-Phenyl-1,2,3,4-tetrahydro-isoquinoline::CHEMBL283105

SMILES C1Cc2cccc(c2CN1)-c1ccccc1

InChI Key InChIKey=MELFXSDLADDYAB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50017045   

TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
G. D. Searle

Curated by ChEMBL
LigandPNGBDBM50017045(8-Phenyl-1,2,3,4-tetrahydro-isoquinoline | CHEMBL2...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to phencyclidine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A)/D(2) dopamine receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50017045(8-Phenyl-1,2,3,4-tetrahydro-isoquinoline | CHEMBL2...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of [3H]haloperidol binding to Dopamine receptor in calf caudate nuclei.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A)/D(2) dopamine receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50017045(8-Phenyl-1,2,3,4-tetrahydro-isoquinoline | CHEMBL2...)
Affinity DataIC50:  1.20E+5nMAssay Description:Inhibition of [3H]dopamine binding to Dopamine receptor in calf caudate nuclei.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
G. D. Searle

Curated by ChEMBL
LigandPNGBDBM50017045(8-Phenyl-1,2,3,4-tetrahydro-isoquinoline | CHEMBL2...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed