BDBM50017101 7,8-Dimethoxy-1,2,3a,4,5,9b-hexahydro-benzo[e]isoindol-3-one::CHEMBL35053
SMILES COc1cc2CC[C@H]3[C@@H](CNC3=O)c2cc1OC
InChI Key InChIKey=QWQNNBPCVVLDDY-GXSJLCMTSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50017101
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Centre De Neurochimie Du Cnrs
Curated by ChEMBL
Centre De Neurochimie Du Cnrs
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of cGMP-PDE phosphodiesterase from bovine aorta using 1 uM cGMP (insignificant)More data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B(Bos taurus)
Centre De Neurochimie Du Cnrs
Curated by ChEMBL
Centre De Neurochimie Du Cnrs
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of phosphodiesterase from bovine aorta with 1 uM cGMP calcium (10 uM) and calmodulin (15 nM) (insignificant)More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Centre De Neurochimie Du Cnrs
Curated by ChEMBL
Centre De Neurochimie Du Cnrs
Curated by ChEMBL
Affinity DataIC50: 1.38E+5nMAssay Description:Inhibitory activity against phosphodiesterase was determined in vitro using bovine aorta, at 1 uM cAMP for cAMP-PDE.More data for this Ligand-Target Pair