BDBM50017104 7,8-Dimethoxy-1,2,3a,4,5,9b-hexahydro-benzo[e]isoindol-3-one::CHEMBL32807

SMILES COc1cc2CC[C@@H]3[C@@H](CNC3=O)c2cc1OC

InChI Key InChIKey=QWQNNBPCVVLDDY-MWLCHTKSSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50017104   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Centre De Neurochimie Du Cnrs

Curated by ChEMBL
LigandPNGBDBM50017104(7,8-Dimethoxy-1,2,3a,4,5,9b-hexahydro-benzo[e]isoi...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory activity against phosphodiesterase was determined in vitro using bovine aorta, at 1 uM cGMP for cGMP-PDE;Compound is insignificant.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50017104(7,8-Dimethoxy-1,2,3a,4,5,9b-hexahydro-benzo[e]isoi...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory activity against cAMP phosphodiesterase was determined in vitro using bovine aorta, at 1 uM cGMP in the presence of calcium (10 uM) and ca...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Centre De Neurochimie Du Cnrs

Curated by ChEMBL
LigandPNGBDBM50017104(7,8-Dimethoxy-1,2,3a,4,5,9b-hexahydro-benzo[e]isoi...)
Affinity DataIC50:  2.20E+5nMAssay Description:Inhibitory activity against phosphodiesterase was determined in vitro using bovine aorta, at 1 uM cAMP for cAMP-PDE.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed