BDBM50017684 1-hydroxy-14-isopropenyl-13-methyl-(1R,3R,5S,8S,9R,12S,13R,14R)-4,7,10-trioxapentacyclo[6.4.1.19,12.03,5.05,13]tetradecane-6,11-dione::1-hydroxy-14-isopropenyl-13-methyl-(1R,3R,5S,8S,9R,12S,13R,14R)-4,7,10-trioxapentacyclo[6.4.1.19,12.03,5.05,13]tetradecane-6,11-dione(picrotoxin)::3-(1-Methyl-pyrrolidin-2-yl)-pyridine::CHEMBL47244::PICROTOXININ::PICROTOXININ1-hydroxy-14-isopropenyl-13-methyl-(1R,3R,5S,8S,9R,12S,13R,14R)-4,7,10-trioxapentacyclo[6.4.1.19,12.03,5.05,13]tetradecane-6,11-dione(picrotoxinin)::Picrotoxin

SMILES CC(=C)[C@@H]1[C@H]2OC(=O)[C@@H]1[C@]1(O)C[C@H]3O[C@]33C(=O)O[C@H]2[C@]13C

InChI Key InChIKey=PIMZUZSSNYHVCU-YKWPQBAZSA-N

Data  1 IC50

PDB links: 7 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50017684   

TargetGlycine receptor subunit alpha-2(Rattus norvegicus)
Université

Curated by ChEMBL
LigandPNGBDBM50017684(1-hydroxy-14-isopropenyl-13-methyl-(1R,3R,5S,8S,9R...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of rat alpha2 homomeric glycine receptor expressed in CHO cells assessed as inhibition of 300 uM glycine-elicited current by outside patch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed