BDBM50017782 CHEMBL280744::Tetrahydro-pyran-4-carboxylic acid {1-[1-(4-azido-1-cyclohexylmethyl-2,3-dihydroxy-butylcarbamoyl)-2-(3H-imidazol-4-yl)-ethylcarbamoyl]-2-phenyl-ethyl}-amide

SMILES O[C@H](CN=[N+]=[N-])[C@@H](O)[C@@H](CC1CCCCC1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)C1CCOCC1

InChI Key InChIKey=USGGZYYLFZHMLW-LLQHYSMESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50017782   

TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50017782(CHEMBL280744 | Tetrahydro-pyran-4-carboxylic acid ...)
Affinity DataIC50:  7.60nMpH: 7.4Assay Description:Inhibitory activity against purified human plasma renin at pH 6.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50017782(CHEMBL280744 | Tetrahydro-pyran-4-carboxylic acid ...)
Affinity DataIC50:  0.700nMpH: 6.0Assay Description:Inhibitory activity against purified human plasma renin at pH 6.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed