BDBM50019195 CHEMBL73621::[3-(4-Chloro-benzoylamino)-5-(2-fluoro-phenyl)-2-oxo-2,3-dihydro-benzo[e][1,4]diazepin-1-yl]-acetic acid: 0.45NaI.0.75H2O

SMILES OC(=O)CN1c2ccccc2C(=NC(NC(=O)c2ccc(Cl)cc2)C1=O)c1ccccc1F

InChI Key InChIKey=ZAYUQXRGJMLMAM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50019195   

TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50019195(CHEMBL73621 | [3-(4-Chloro-benzoylamino)-5-(2-fluo...)
Affinity DataIC50:  8.20E+3nMAssay Description:Half-maximal inhibition of [125I]gastrin binding to guinea pig gastric glandsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50019195(CHEMBL73621 | [3-(4-Chloro-benzoylamino)-5-(2-fluo...)
Affinity DataIC50:  2.10E+4nMAssay Description:Half-maximal inhibition of [125I]-CCK-8(+) binding to cholecystokinin receptor from guinea pig brain tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50019195(CHEMBL73621 | [3-(4-Chloro-benzoylamino)-5-(2-fluo...)
Affinity DataIC50:  32nMAssay Description:Half-maximal inhibition of [125I]CCK-33 binding to cholecystokinin A receptor from rat pancreatic tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed