BDBM50019389 3-Allyl-6-chloro-1-(4-hydroxy-phenyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::CHEMBL130795

SMILES Oc1ccc(cc1)C1CN(CC=C)CCc2c(Cl)c(O)c(O)cc12

InChI Key InChIKey=VDHWYWSLUYRNGE-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50019389   

TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50019389(3-Allyl-6-chloro-1-(4-hydroxy-phenyl)-2,3,4,5-tetr...)
Affinity DataEC50:  122nMAssay Description:Dopamine receptor D2 agonist activity was determined for inhibition of release of NE in an isolated perfused rabbit ear artery preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50019389(3-Allyl-6-chloro-1-(4-hydroxy-phenyl)-2,3,4,5-tetr...)
Affinity DataEC50:  122nMAssay Description:Tested in vitro for dopamine agonist activity in rabbit ear artery after at a dose of 0.3 mg/kgMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50019389(3-Allyl-6-chloro-1-(4-hydroxy-phenyl)-2,3,4,5-tetr...)
Affinity DataEC50:  15nMAssay Description:Dopamine agonist (Dopamine receptor D1) activity was measured as increase in cAMP formation relative to maximum increase in dopamine-sensitive adenyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed