BDBM50019900 CHEMBL3287205::US9533999, i-5

SMILES Fc1ccc(CN2C(=O)CS(=O)(=O)c3cccnc23)cc1OC(F)(F)F

InChI Key InChIKey=AARWDDKVRQFBKD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50019900   

TargetIntermediate conductance calcium-activated potassium channel protein 4(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM50019900(CHEMBL3287205 | US9533999, i-5)
Affinity DataIC50:  49nMAssay Description:HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIntermediate conductance calcium-activated potassium channel protein 4(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM50019900(CHEMBL3287205 | US9533999, i-5)
Affinity DataIC50:  49nMAssay Description:Inhibition of human KCa3.1 overexpressed in HEK293 cells assessed as thallium influx preincubated for 15 mins followed by thallium/ionomycin addition...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed