BDBM50019939 CHEMBL3287569

SMILES Cc1cc(Cl)ccc1-c1cccc(COc2ccc(cc2)[C@H](CC(O)=O)c2nccn2C)c1

InChI Key InChIKey=GFFXCPIMXLSUGF-VWLOTQADSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50019939   

TargetFree fatty acid receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50019939(CHEMBL3287569)
Affinity DataEC50:  33nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells by aequorin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50019939(CHEMBL3287569)
Affinity DataEC50:  7.60nMAssay Description:Agonist activity at human GPR40 expressed in mouse A9 cells by inositol phosphate accumulation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Macaca fascicularis)
Amgen

Curated by ChEMBL
LigandPNGBDBM50019939(CHEMBL3287569)
Affinity DataEC50:  29nMAssay Description:Agonist activity at cynomolgus monkey GPR40 in presence of 0.01% human serum albumin relative to AMG 837More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50019939(CHEMBL3287569)
Affinity DataEC50:  33nMAssay Description:Partial agonist activity at human GPR40 expressed in CHO cells measured over 20 secs interval by luminometric analysis in presence of 0.01% human ser...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Rattus norvegicus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50019939(CHEMBL3287569)
Affinity DataEC50:  640nMAssay Description:Agonist activity at rat GPR40 in presence of 0.01% human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50019939(CHEMBL3287569)
Affinity DataEC50:  1.00E+4nMAssay Description:Partial agonist activity at human GPR40 expressed in CHO cells measured over 20 secs interval by luminometric analysis in presence of 100% human seru...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed