BDBM50020102 5-Amino-2-{4-[(2,4-diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-pentanoic acid::CHEMBL28049

SMILES CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(cc1)C(=O)N[C@@H](CCCN)C(O)=O

InChI Key InChIKey=XZMFYMLGNMSYOG-AWEZNQCLSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50020102   

TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50020102(5-Amino-2-{4-[(2,4-diamino-pteridin-6-ylmethyl)-me...)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibitory constant against purified Folyl-polyglutamate synthase obtained from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFolylpolyglutamate synthase, mitochondrial(Mus musculus)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50020102(5-Amino-2-{4-[(2,4-diamino-pteridin-6-ylmethyl)-me...)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibitory constant against purified Folyl-polyglutamate synthase obtained from ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFolylpolyglutamate synthase, mitochondrial(Mus musculus)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50020102(5-Amino-2-{4-[(2,4-diamino-pteridin-6-ylmethyl)-me...)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibitory constant against purified Folyl-polyglutamate synthase obtained from mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed